Department of ImmunoPathology

Subjects:

1. Molecular regulation of immune responses.
2. Physiological and pathological roles of guidance factors.

Published Papers

1. Involvement of Sema4A in the progression of experimental autoimmune myocarditis.

   Nobuhiko Makino, Toshihiko Toyofuku, Noriko Takegahara, Hyota Takamatsu, Tatsusada Okuno, Yukinobu Nakagawa, Sujin Kang, Satoshi Nojima, Masatsugu Hori, Hitoshi Kikutani and Atsushi Kumanogoh

   FEBS Lett, 582 (28), 3935-3940, 2008.
2. Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.

   Quenten Schwarz, Kathryn E Waimey, Matthew Golding, Hyota Takamatsu, Atsushi Kumanogoh, Hajime Fujisawa, Hwai-Jong Cheng and Christiana Ruhrberg

   Dev Biol, 324 (1), 1-9, 2008.
3. Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.

   Toshihiko Toyofuku, Junko Yoshida, Tamiko Sugimoto, Midori Yamamoto, Nobuhiko Makino, Hyota Takamatsu, Noriko Takegahara, Fumikazu Suto, Masatsugu Hori, Hajime Fujisawa, Atsushi Kumanogoh and Hitoshi Kikutani

   Dev Biol, 321 (1), 251-262, 2008.
4. Edaravone, a free radical scavenger, ameliorates experimental autoimmune encephalomyelitis.

   Masayuki Moriya, Yuji Nakatsuji, Katsuichi Miyamoto, Tatsusada Okuno, Makoto Kinoshita, Atsushi Kumanogoh, Susumu Kusunoki and Saburo Sakoda

   Neurosci Lett, 440 (3), 323-326, 2008.
5. Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages.

   Jose Rafael Sierra, Simona Corso, Luisa Caione, Virna Cepero, Paolo Conrotto, Alessandro Cignetti, Wanda Piacibello, Atsushi Kumanogoh, Hitoshi Kikutani, Paolo Maria Comoglio, Luca Tamagnone and Silvia Giordano

   J Exp Med, 205 (7), 1673-1685, 2008.
6. Bimodal regulation of T cell-mediated immune responses by TIM-4.

   Masayuki Mizui, Takashi Shikina, Hisashi Arase, Kazuhiro Suzuki, Teruhito Yasui, Paul D Rennert, Atsushi Kumanogoh and Hitoshi Kikutani

   Int Immunol, 20 (5), 695-708, 2008.
7. Plexin-A4 negatively regulates T lymphocyte responses.

   Midori Yamamoto, Kazuhiro Suzuki, Tatsusada Okuno, Takehiro Ogata, Noriko Takegahara, Hyota Takamatsu, Masayuki Mizui, Masahiko Taniguchi, Alain Chédotal, Fumikazu Suto, Hajime Fujisawa, Atsushi Kumanogoh and Hitoshi Kikutani

   Int Immunol, 20 (3), 413-420, 2008.
8. Semaphorins and their receptors in immune cell interactions.

   Kazuhiro Suzuki, Atsushi Kumanogoh and Hitoshi Kikutani

   Nat Immunol, 9 (1), 17-23, 2008.

Link

http://www.biken.osaka-u.ac.jp/