Department of ImmunoPathology

Subjects:

1. Molecular regulation of immune responses.
2. Physiological and pathological roles of guidance factors.

Published Papers

1. A novel role for the semaphorin Sema4D in the induction of allo-responses.

   Raimon Duran-Struuck, Isao Tawara, Kathi Lowler, Shawn G Clouthier, Elizabeth Weisiger, Clare Rogers, Gary Luker, Atsushi Kumanogoh, Chen Liu, James L M Ferrara and Pavan Reddy

   Biol Blood Marrow Transplant, 13 (11), 1294-1303, 2007.
2. CD83 influences cell-surface MHC class II expression on B cells and other antigen-presenting cells.

   Yoshihiro Kuwano, Charlene M Prazma, Norihito Yazawa, Rei Watanabe, Nobuko Ishiura, Atsushi Kumanogoh, Hitoshi Okochi, Kunihiko Tamaki, Manabu Fujimoto and Thomas F Tedder

   Int Immunol, 19 (8), 977-992, 2007.
3. Tim2 is expressed in mouse fetal hepatocytes and regulates their differentiation.

   Natsumi Watanabe, Minoru Tanaka, Kaori Suzuki, Atsushi Kumanogoh, Hitoshi Kikutani and Atsushi Miyajima

   Hepatology, 45 (5), 1240-1249, 2007.
4. Immune semaphorins: increasing members and their diverse roles.

   Hitoshi Kikutani, Kazuhiro Suzuki and Atsushi Kumanogoh

   Adv Immunol, 93, 121-143, 2007.
5. Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin.

   Kazuhiro Suzuki, Tatsusada Okuno, Midori Yamamoto, R Jeroen Pasterkamp, Noriko Takegahara, Hyota Takamatsu, Tomoe Kitao, Junichi Takagi, Paul D Rennert, Alex L Kolodkin, Atsushi Kumanogoh and Hitoshi Kikutani

   Nature, 446 (7136), 680-684, 2007.
6. Semaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1.

   Toshihiko Toyofuku, Masanori Yabuki, Junko Kamei, Motohiro Kamei, Nobuhiko Makino, Atsushi Kumanogoh and Masatsugu Hori

   EMBO J, 26 (5), 1373-1384, 2007.
7. Serum chemokine profile in patients with bullous pemphigoid.

   H Nakashima, M Fujimoto, N Asashima, R Watanabe, Y Kuwano, N Yazawa, N Maruyama, H Okochi, A Kumanogoh and K Tamaki

   Br J Dermatol, 156 (3), 454-459, 2007.
8. Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury.

   Li Zhu, Wolfgang Bergmeier, Jie Wu, Hong Jiang, Timothy J Stalker, Marcin Cieslak, Ran Fan, Laurence Boumsell, Atsushi Kumanogoh, Hitoshi Kikutani, Luca Tamagnone, Denisa D Wagner, Marcos E Milla and Lawrence F Brass

   Proc Natl Acad Sci U S A, 104 (5), 1621-1626, 2007.

Link

http://www.biken.osaka-u.ac.jp/