Genome Dynamics Group

Subjects:

1. Molecular mechanisms of maintenance of genome stability.
2. Molecular mechanisms of DNA homologous recombination, repair and replication.
3. Molecular analysis of chromosomal DNA dynamics.

Published Papers

1. Rhp51-Dependent Recombination Intermediates That Do Not Generate Checkpoint Signal Are Accumulated in Schizosaccharomyces pombe rad60 and smc5/6 Mutants after Release from Replication Arrest.

   Izumi Miyabe, Takashi Morishita, Takashi Hishida, Shuji Yonei and Hideo Shinagawa

   Mol Cell Biol, 26 (1), 343-353, 2006.
2. Degradation of Escherichia coli RecN aggregates by ClpXP protease and its implications for DNA damage tolerance.

   Kohji Nagashima, Yoshino Kubota, Tatsuya Shibata, Chikako Sakaguchi, Hideo Shinagawa and Takashi Hishida

   J Biol Chem, 281 (41), 30941-30946, 2006.
3. Direct observation of DNA rotation during branch migration of Holliday junction DNA by Escherichia coli RuvA-RuvB protein complex.

   Yong-Woon Han, Tomomi Tani, Masahito Hayashi, Takashi Hishida, Hiroshi Iwasaki, Hideo Shinagawa and Yoshie Harada

   Proc Natl Acad Sci U S A, 103 (31), 11544-11548, 2006.
4. Functional and physical interaction of yeast Mgs1 with PCNA: impact on RAD6-dependent DNA damage tolerance.

   Takashi Hishida, Tomoko Ohya, Yoshino Kubota, Yusuke Kamada and Hideo Shinagawa

   Mol Cell Biol, 26 (14), 5509-5517, 2006.

Link

http://www.biken.osaka-u.ac.jp/