Department of Viral Infections

Subjects:

1. Analysis of host genetic factors affecting disease courses of human immunodeficiency virus (HIV) infection.
2. Studies on chemokines and chemokine receptors.
3. Analysis of molecular mechanisms of HIV entry into target cells.
4. Analysis of molecular mechanisms of HIV virion formation.
5. Development of a novel vector system based on Sendai virus.

Published Papers

1. A specific region of 37 amino acid residues in the SPRY (B30.2) domain of African green monkey TRIM5alpha determines species-specific restriction of simian immunodeficiency virus SIVmac infection.

   Emi E Nakayama, Hiroyuki Miyoshi, Yoshiyuki Nagai and Tatsuo Shioda

   J Virol, 79 (14), 8870-8877, 2005.
2. Influence of Glycosylation on the Efficacy of an Env-Based Vaccine against Simian Immunodeficiency Virus SIVmac239 in a Macaque AIDS Model.

   Kazuyasu Mori, Chie Sugimoto, Shinji Ohgimoto, Emi E Nakayama, Tatsuo Shioda, Shigeru Kusagawa, Yutaka Takebe, Munehide Kano, Tetsuro Matano, Takae Yuasa, Daisuke Kitaguchi, Masaaki Miyazawa, Yumiko Takahashi, Michio Yasunami, Akinori Kimura, Naoki Yamamoto, Yasuo Suzuki and Yoshiyuki Nagai

   J Virol, 79 (16), 10386-10396, 2005.

Link

http://www.biken.osaka-u.ac.jp/