Department of Molecular Genetics

Subjects:

1. Molecular mechanisms regulating the cell cycle in mammalian cells.
2. Molecular mechanisms controlling the meiosis in fission yeast.
3. Molecular mechanisms modulating the metastasis of malignant cells.
4. Application of a new technique (stepwise subtraction) to RNA diagnosis.

Published Papers

1. Isolation and expression profiling of genes upregulated in the peripheral blood cells of systemic lupus erythematosus patients.

   Taeko Ishii, Hiroaki Onda, Akie Tanigawa, Shiro Ohshima, Hiroshi Fujiwara, Toru Mima, Yoshinori Katada, Hitoshi Deguchi, Masaki Suemura, Tadao Miyake, Kunio Miyatake, Ichiro Kawase, Hanjun Zhao, Yoshiaki Tomiyama, Yukihiko Saeki and Hiroshi Nojima

   DNA Res, 12 (6), 429-439, 2005.
2. Cyclin G1 and cyclin G2 are expressed in the periimplantation mouse uterus in a cell-specific and progesterone-dependent manner: evidence for aberrant regulation with Hoxa-10 deficiency.

   Limin Yue, Takiko Daikoku, Xiaonan Hou, Meiling Li, Haibin Wang, Hiroshi Nojima, Sudhansu K Dey and Sanjoy K Das

   Endocrinology, 146 (5), 2424-2433, 2005.
3. A B56 regulatory subunit of protein phosphatase 2A localizes to nuclear speckles in cardiomyocytes.

   Marisa S Gigena, Akihiko Ito, Hiroshi Nojima and Terry B Rogers

   Am J Physiol Heart Circ Physiol, 289 (1), H285-294, 2005.
4. Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway.

   Ippei Nagamori, Norikazu Yabuta, Takayuki Fujii, Hiromitsu Tanaka, Kentaro Yomogida, Yoshitake Nishimune and Hiroshi Nojima

   Genes Cells, 10 (6), 575-594, 2005.
5. Mcp6, a meiosis-specific coiled-coil protein of Schizosaccharomyces pombe, localizes to the spindle pole body and is required for horsetail movement and recombination.

   Takamune T Saito, Takahiro Tougan, Daisuke Okuzaki, Takashi Kasama and Hiroshi Nojima

   J Cell Sci, 118 (Pt 2), 447-459, 2005.

Link

http://www.biken.osaka-u.ac.jp/