Department of Immunochemistry

Subjects:

1. Role of paired receptors on host defense.
2. Mechanism of activation of NK cells.

Published Papers

1. Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR).

   Satoru Ishikawa, Noriko Arase, Tadashi Suenaga, Yoshitomo Saita, Masaki Noda, Takayuki Kuriyama, Hisashi Arase and Takashi Saito

   Int Immunol, 16 (7), 1019-1025, 2004.
2. NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling.

   Makoto Ohtsuka, Hisashi Arase, Arata Takeuchi, Sho Yamasaki, Ritsuko Shiina, Tadahiro Suenaga, Daiju Sakurai, Tadashi Yokosuka, Noriko Arase, Makio Iwashima, Toshio Kitamura, Hideshige Moriya and Takashi Saito

   Proc Natl Acad Sci U S A, 101 (21), 8126-8131, 2004.
3. Specific recognition of virus-infected cells by paired NK receptors.

   Hisashi Arase and Lewis L Lanier

   Rev Med Virol, 14 (2), 83-93, 2004.
4. Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors.

   James R Carlyle, Amanda M Jamieson, Stephan Gasser, Christopher S Clingan, Hisashi Arase and David H Raulet

   Proc Natl Acad Sci U S A, 101 (10), 3527-3532, 2004.
5. Activation of natural killer cells and dendritic cells upon recognition of a novel CD99-like ligand by paired immunoglobulin-like type 2 receptor.

   Ikuo Shiratori, Kouetsu Ogasawara, Takashi Saito, Lewis L Lanier and Hisashi Arase

   J Exp Med, 199 (4), 525-533, 2004.
6. Fc epsilon RI gamma-ITAM is differentially required for mast cell function in vivo.

   Daiju Sakurai, Sho Yamasaki, Kanako Arase, Seung Yong Park, Hisashi Arase, Akiyoshi Konno and Takashi Saito

   J Immunol, 172 (4), 2374-2381, 2004.

Link

http://www.biken.osaka-u.ac.jp/