Laboratory of Prevention of Viral Diseases

Subjects:

1. Characterization of recombinant influenza viral neuraminidase expressed in CHO cells.
2. Estimation of neuraminidase contents of influenza viruses and split-products vaccines.

Papers published in 2003

1. Protective mucosal immunity in aging is associated with functional CD4+ T cells in nasopharyngeal-associated lymphoreticular tissue.

   Yukari Hagiwara, Jerry R McGhee, Keiko Fujihashi, Ryoki Kobayashi, Naoto Yoshino, Kosuke Kataoka, Yuri Etani, Mi-Na Kweon, Shinichi Tamura, Takeshi Kurata, Yoshifumi Takeda, Hiroshi Kiyono and Kohtaro Fujihashi

   J Immunol, 170 (4), 1754-1762, 2003.
2. Roles of anti-hemagglutinin IgA and IgG antibodies in different sites of the respiratory tract of vaccinated mice in preventing lethal influenza pneumonia.

   Reiko Ito, Yasuko Asahi Ozaki, Tomoki Yoshikawa, Hideki Hasegawa, Yuko Sato, Yujiro Suzuki, Ryosuke Inoue, Tsuneo Morishima, Naomi Kondo, Tetsutaro Sata, Takeshi Kurata and Shin-ichi Tamura

   Vaccine, 21 (19-20), 2362-2371, 2003.
3. Protection against influenza virus infection by intranasal administration of C3d-fused hemagglutinin.

   Izumi Watanabe, Ted M Ross, Shin-ichi Tamura, Takeshi Ichinohe, Satoshi Ito, Hidehiro Takahashi, Hirofumi Sawa, Joe Chiba, Takeshi Kurata, Tetsutaro Sata and Hideki Hasegawa

   Vaccine, 21 (31), 4532-4538, 2003.
4. [Present situation of influenza vaccine development]

   Shin-ichi Tamura

   Nippon Rinsho, 61 (11), 1993-2000, 2003.

Link

http://www.biken.osaka-u.ac.jp/